breakthrough in the treatment of heart attacks?
when testing an experimental drug, a new drug reduced the heart damage after a heart attack by up to 60 percent. Doctors hope that a future application can significantly improve the survival rate of people after a heart attack.
In their current study,
the research team of at Imperial College London and the internationally highly recognised University of Oxford found that a new experimental drug can significantly reduce heart damage after a Herzinfakrt. The experts released the results of their study in the English-language journal “Cell Stem Cell”.
is the new drug be already available in the year 2021?
the new drug can block harmful chemical signals that occur when the blood supply to the heart is interrupted. In such a case, the lack of oxygen then releases chemicals that can lead to the death of tissue sections and heart failure, which additionally increases the risk of further heart attacks or strokes. The experts hope that the experimental drug will have completed all necessary safety tests and patient trials by the year 2021, to revolutionize the supply then after heart attacks. The search for a drug that could limit damage to the heart muscle during and after a heart attack and stop a heart failure, is an important research goal, for decades, the scientists say. But despite a number of promising candidates in the past, there are still no medications, which can do this in the clinical routine. Should the drug to work as doctors hope, it will represent a real revolution in the treatment of heart attacks.
what is a heart failure?
the new drug works by it targets a protein called MAP4K4, that scientists in the study of people with heart failure as a particularly important have classified. A congestive heart failure means that the heart does not properly can pump blood through the body, often because the muscle has become too weak or too stiff. But, a heart failure does not mean that the heart has stopped working completely. A congestive heart failure can occur at any age, but is most common in the elderly. Heart failure is a long-term illness that deteriorates gradually with time. Can usually not completely cure the disease, but the symptoms can be controlled often for many years well.
which indicates a heart failure?
these symptoms indicate a heart failure: breathlessness after activity, shortness of breath at rest, frequent fatigue and swollen ankles and legs. Other symptoms in some people, such as persistent cough, an accelerated heart rate and dizziness. The symptoms can develop quickly or gradually over a period of weeks or months. Always consult your doctor, if the symptoms of heart failure persists or deteriorate gradually, doctors advise.
damage could be reduced by two-thirds after heart attack
researchers have found that MAP4K4 is activated after a heart attack in the tissue of mice and men and then irreparably damages the heart and other body tissues. By blocking its activity in human tissue in a heart attack produced by the lab, the team was able to reduce this loss by almost two-thirds.
effects of heart attack
when someone has a heart attack, the blood supply of the body is interrupted or reduced, causing lack of oxygen. This lack of oxygen, raises chemical stress signals, which can then cause the death of cells. If parts of the heart cells die off, the muscle is weaker and less well is able to pump blood through the body. If the patient survives the attack, this has lifelong effects on health. (as)